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Counting Number and Time by Mammalian Stem Cells

日期: 2019-05-14
the Mini-Symposium: Neural development and function
Topic 1: Counting Number and Time by Mammalian Stem Cells
Speaker: Weimin Zhong, Ph.D
Time: 13:00-14:30, May 21, 2019
Venue:  3 floor lobby, Lui Che Woo Building
Host: Prof. Yulong Li
Abstract:
Weimin Zhong, Ph.D., is an Associate Professor in the Department of Molecular, Cellular and Developmental Biology at Yale University. He attended Peking University as an undergraduate (premed) from 1981-1984 and studied medicine at Peking Union Medical College from 1984-1988. He joined the graduate program at The Rockefeller University afterwards, receiving Ph.D. in 1993. After postdoctoral training at University of California, San Francisco, he joined the Yale faculty in 1999. His laboratory uses the mammalian Numb proteins, Numb and Numbl, as entry point, and neurogenesis and mammary gland development in mice as model systems, to probe the contribution of two modes of cell division – symmetric vs. asymmetric – in regulating stem cell behavior, particularly probing why stem cells in mammals cannot repair damages that go beyond the normal wear and tear. Current research examines the hypothesis that multiple factors – through independent pathways that regulate the number and the temporal competence of stem cells – place fundamental constrains on their ability to repair tissue damages, seeking to identify molecular components that specify the fates, count the number and regulate the competence of neural and other stem cells.
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